CTX-M-10 linked to a phage-related element is widely disseminated among Enterobacteriaceae in a Spanish hospital.

نویسندگان

  • Antonio Oliver
  • Teresa M Coque
  • Diana Alonso
  • Aránzazu Valverde
  • Fernando Baquero
  • Rafael Cantón
چکیده

CTX-M-10 has been widely disseminated among multiple clones of several species of Enterobacteriaceae, harboring seemingly different plasmids, for over a decade in Ramón y Cajal University Hospital, Madrid, Spain. Cloning and sequencing of a 12.2-kb DNA fragment from plasmid pRYCE21 from Klebsiella pneumoniae strain KP4aC revealed a novel phage-related element immediately upstream of bla(CTX-M-10) conserved among different CTX-M-10-producing strains. This is the first report showing an extended-spectrum-beta-lactamase gene linked to a phage-related element.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 49 4  شماره 

صفحات  -

تاریخ انتشار 2005